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Other than Phony-positive outcomes, heterophile antibodies may cause falsely minimal results if they bind into the variable areas of your seize antibody, mimicking the antigen to be measured and blocking troponin from binding.[89] The most often made use of procedure for minimizing the impact of HAMA on business immunoassays may be the addition of non-immune mouse immunoglobulin (IgG).
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Cardiac troponin T to be a marker for myocardial ischemia in sufferers noticed in the crisis Section deposit pulsa for acute chest discomfort.[Am Coronary heart J. 1999]
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Results could be confounded if there is very poor preanalytical dealing with of troponin specimens, which include incomplete sample mixing at some time of specimen collection, inadequate sample centrifugation and separation of crimson cells from serum or plasma, existence of fibrin resulting from incomplete serum separation, and so on.
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